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3.2c Animations

Antibody11. The Arizona Biology Project: Antibody Structure Tutorial - Animations The two animation links below reinforce the content presented in the Antibody Structure Tutorial you just completed.

 

 

 

a. This first animation displays the overlapping beta sheets of the FR (framework) region joined to the HV (hypervariable) region of the antibody.
Animation: FR and HV regions of antibody
(www.biology.arizona.edu, Multimedia Page)

b. This second animation displays the three dimensional interaction between an antibody and an antigen. It is the HV regions of the antibody that interact with the surface of the antigen. Animation: Antigen interacts with HV region c. This third animation displays a molecular simulation of a specific example of an antibody interacting with an antigen. The anitigen is hen egg white lysozyme and it contains the unique structure of the amino acid, glutamine at position 121 that the antibody’s HV region interacts with.
Animation: Gln 121 of lysozyme surrounded by amino acid residues of antibody
(www.biology.arizona.edu, Multimedia Page)


121

2. Antibody Animated Tutorial – Making a Monoclonal Antibody (Sumanas Inc.) You may view the animated tutorials provided on the website in a slide-by-slide version that you navigate through or in a narrated version that navigates for you.




Animation
(www.sumanasinc.com, Multimedia Page)





121a3. Monoclonal Antibody Production Animations from Raven, Johnson, Losos, & Singer, Biology, 7th Edition, 2005 Click on the following link to view an animation about how monoclonal antibodies are produced. The animation provides a narration as well as guided text to support the simulation.






Animation
(highered.mcgraw-hill.com, Multimedia Page)




Antibody24. IgE Mediated (Type I) Hypersensitivity Animations from Raven, Johnson, Losos, & Singer, Biology, 7th Edition, 2005 Click on the following link to view an animation about how hypersensitivities (or allergic responses) are mediated by one specific type of antibody known as Immunoglobulin (Ig) E. The animation depicts the interaction between antibodies (specifically IgE) and antigens (specifically allergens) and also depicts the roles of and interactions between B and T cells of the immune system in the hypersensitivity reaction. The animation provides a narration as well as guided text to support the simulation.


Animation
(highered.mcgraw-hill.com, Multimedia Page)

 

 
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